π‘οΈ Immune Modulation
7 peptides in this category
Crystagen
Crystagen is a thymic-derived peptide bioregulator that modulates immune function, supports thymic repair, and enhances lymphocyte output. It is administered orally and has been shown in Eastern European research to improve immune performance in aging and immunosuppressed individuals.
1β2 capsules daily for 10β30 days depending on immune status. Repeat 2β3x per year.
LL-37
LL-37 is a naturally occurring antimicrobial peptide in the cathelicidin family, integral to innate immune defense. It exerts antimicrobial, immunomodulatory, and wound-healing effects through membrane disruption, immune activation, and epithelial regeneration. Its applications span infectious disease, chronic wounds, and immune regulation.
200 mcg SubQ daily or topical application 1β2x daily to affected site. Research-based; clinical protocols still under development.
KPV
KPV (Lys-Pro-Val) is a tripeptide derived from alpha-MSH with strong anti-inflammatory, antimicrobial, and antifungal properties. It is being explored for use in inflammatory bowel diseases, topical inflammatory skin conditions, and systemic inflammation. Multiple delivery routes have been studied, including oral, SubQ, and topical forms.
250β500 mcg oral or SubQ daily. Topical: 2% KPV cream applied twice daily to affected areas.
Thymosin Alpha-1
Thymosin Alpha-1 (TΞ±1) is a synthetic peptide that enhances the immune system's ability to defend against infections, tumors, and chronic inflammation. It is widely studied for its immunomodulatory effects in cancer therapy, hepatitis, HIV, and other conditions involving immune suppression. Though not FDA-approved in the U.S., it is approved in several countries for adjuvant use in immunocompromised patients.
1.6 mg SubQ 2β3 times per week for 6β12 weeks; long-term maintenance use evaluated in chronic viral and immune disorders.
Thymogen
Thymogen is a thymic-derived short peptide immunomodulator that promotes T-cell activity, immune rebalancing, and resistance to infection. It is widely used in Eastern European protocols to support immune function, particularly in cases of immunodeficiency, chronic infection, or age-related immune decline.
Standard dose: 100 mcg SQ once daily for 10β14 days. Range: 50β300 mcg daily. Repeat cycle every 3β6 months based on immune health status. Pediatric dosing is age-based (not weight-based): ages 1β3: 10β20 mcg; ages 4β6: 20β30 mcg; ages 7β14: 50 mcg; adults: 100 mcg.
Thymalin
Thymalin is a thymic peptide complex known for its potent immunoregulatory effects, supporting T-cell maturation, reducing inflammation, and improving thymic function. It has been investigated for anti-aging, immune optimization, and cancer adjunctive support.
10 mg SubQ daily for 5β10 days, repeated in 2β3 cycles annually. Maintenance protocols use 1β2x weekly for immune health.
VIP
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide that modulates immune response, dilates pulmonary vessels, and protects neural tissue. It is being studied for its potential role in treating pulmonary hypertension, COVID-19 respiratory failure, inflammatory and autoimmune disorders, and migraines.
Intranasal (primary route): 50 mcg/spray, 1 spray per nostril 3β4x daily (200β400 mcg total/day). Titrate from 50 mcg 2x daily β 100 mcg 4x daily over 2β4 weeks. SQ (off-label): 100 mcg daily for 4β6 weeks in autoimmune or pulmonary protocols. Used in CIRS, MCAS, and neuroinflammation management.