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Crystagen

Immune Modulation

Crystagen is a thymic-derived peptide bioregulator that modulates immune function, supports thymic repair, and enhances lymphocyte output. It is administered orally and has been shown in Eastern European research to improve immune performance in aging and immunosuppressed individuals.

Administration
Oral
capsules capsule/tablet
Daily Range
1–3 capsules Oral
Daily
Standard Dose
2 capsules
Cycle
4–8 weeks
then reassess
Crystagenimmune peptidethymus bioregulatororal peptidecytogen

Dosing Guide

Administered at 100–200 μg per day in studies. Clinical use is not authorized.

Standard / Gradual Approach

standard
PhaseDose
Week 11000 mcg (1 mg)
Week 21500 mcg (1.5 mg)
Weeks 3–122000 mcg (2 mg)

Protocol Summary

Oral: Daily · Dose range 1–3 capsules with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending

Frequency & Cycling

Oral

Typical course: 10–30 days of daily dosing. Repeat up to 2–3x per year for immune maintenance.

💊 Quick Start

Starting Dose
1000 mcg (1 mg) (15 units (0.15 mL))
Maintenance Dose
2000 mcg (2 mg) (30 units (0.30 mL))

Potential Benefits & Use Cases

Crystagen is a thymic bioregulatory peptide not approved for clinical use. For research only.
May support immune system modulation through thymic bioregulatory peptide mechanisms (preclinical)
Preserves thymic cortex-medulla division and stimulates thymocyte proliferation in irradiated rats (preclinical)
Normalized immunogram in 82% of elderly patients — increased CD3+ and CD4+ cells, normalized CD4+/CD8+ ratio (limited human data)
Clinical data Strong preclinical Limited data

Mechanism of Action

→Normalizes thymus-derived peptide signaling pathways
→Stimulates lymphocyte differentiation and cytokine balance
→Restores immune regulatory gene expression in aged individuals

Stacking Synergies

+
Thymosin Alpha-1
Synergistic T-cell activation and immune rejuvenation with Thymosin Alpha-1
+
Thymogen
Immune modulation enhanced when paired with Thymogen

Lifestyle & Optimization

diet

Balanced nutrient-dense diet. Stay hydrated.

sleep

Adequate sleep (7–9 hours). Manage stress.

timing

Consistent daily dosing.

exercise

Regular physical activity.

Peptide Research & Preclinical Studies

Evidence-Based Research Findings

Study TitleType
NBINNO — Thymalin Peptide: A Beginner's Guide to Benefits, Dosage, and AdministrationReference
DTS Pharmacy — Crystagen Peptide product informationReference
Peptide Shop — THYMOGEN-10: Synthesized peptide for immune systemReference
e-Peptide — THYMALIN: Natural thymic peptide for immune systemReference
Sigma-Aldrich — Peptide Handling GuideReference
Peptide Sciences — Peptide Storage: Best practicesReference
Arpovo Health — How to Store BAC Water After OpeningReference
Hann's Pharmacy — How to Measure With an Insulin SyringeReference

Side Effects & Safety

🧬

Bioavailability & Absorption

SubQ Injection
Not applicable to this compound
Oral Administration
Formulated for oral delivery via capsule; effective for gene modulation at low doses
Half-Life
Not published; effects persist through gene expression regulation
Degradation
Metabolized via standard proteolytic peptide pathways
Tissue Specificity
Thymus, lymph nodes, and peripheral immune cells
⚗️

Peptide Details

Molecular Weight
467.57
Formula
C23H37N5O6
Sequence
Ala-Glu-Asp-Gly
⚖️

Legal Status & Regulatory

RegionStatus
EUNot Approved
FDANot Approved
CanadaNot Approved
AustraliaNot Approved

Storage Instructions

Lyophilized (Powder)
refrigerate at 4 °C (39.2 °F) or freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 4 °C (39.2 °F) for up to 30 days
Reconstituted (Mixed)
Refrigerate at 4 °C (39.2 °F); stable for approximately 30 days