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Thymalin
Immune ModulationThymalin is a thymic peptide complex known for its potent immunoregulatory effects, supporting T-cell maturation, reducing inflammation, and improving thymic function. It has been investigated for anti-aging, immune optimization, and cancer adjunctive support.
Reconstitute
3 mL BAC + 10mg vial
33 mcg/unit
Daily Range
5–20 mg Subcutaneous (SQ)
daily
Standard Dose
10 mg
Cycle
4–8 weeks
then reassess
Thymalinimmunomodulatorythymic peptideanti-agingT-cell stimulation
Dosing & Reconstitution Guide
In clinical studies abroad, doses of 5–10 mg daily for 5–10 days have been used. These regimens are not approved by the FDA or other major regulatory bodies.
Standard / Gradual Approach
10mg VialstandardPhaseDoseVolume
Week 12.5mg75 units
Week 25mg150 units
Week 37.5mg225 units
Week 410mg300 units
Protocol Summary
Subcutaneous (SQ): daily · Dose range 5–20 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
SubQ Injection
Initial loading: 10 mg daily for 5–10 days. Maintenance: 1–2x weekly for 6–12 weeks. Repeat up to 3 cycles annually for immune support and thymic rejuvenation.
🧪 Quick Start
Vial Size
10 mg
BAC Water
3 mL
Concentration
3300 mcg/unit
Potential Benefits & Use Cases
Thymalin is not FDA-approved and is available only for research or regulated international medical use.
Studied for immune normalization in aged animal models
May promote thymus regeneration and T-cell development
Investigated for supporting hematopoietic stem cell activity
Explored for lifespan extension in rodents
Evaluated in clinical settings in Russia for immunosenescence
Potential synergy with Thymosin Alpha-1 (TA1), Zinc, and BPC-157 for immune optimization
Clinical data Strong preclinical Limited data
Mechanism of Action
→Modulates immune cell activity by enhancing T-cell differentiation and thymic function
→Reduces systemic inflammation by suppressing pro-inflammatory cytokines
→Supports thymus gland function, crucial for maintaining immune homeostasis during aging
→Zinc-dependent activity: Thymulin requires sufficient zinc levels for optimal biological activity
Stacking Synergies
+
Thymosin Alpha-1
Enhanced immune function and inflammation modulation
Lifestyle & Optimization
diet
Antioxidant-rich foods for immune support.
sleep
Sleep 7–9 hours nightly for immune optimization. Manage stress through relaxation techniques.
timing
Consistent dosing schedule.
exercise
Exercise moderately 3–4 times weekly.
Peptide Research & Preclinical Studies
Evidence-Based Research Findings
Side Effects & Safety
Common Side Effects
• Localized pain at injection site
Contraindications & Warnings
• Use under medical supervision in patients with serious immune disorders
Long-Term Safety Data
• No known long-term issues with clinical use
🧮 Dose Calculator
Concentration
33.3
mcg/unit
Draw Volume
15
units (0.150 mL)
For a 500 mcg dose, draw 15 units on a U-100 insulin syringe
🧬
Bioavailability & Absorption
SubQ Injection
Effective due to direct entry into the bloodstream for systemic immune modulation.
Oral Administration
Low oral bioavailability due to degradation in the GI tract.
Half-Life
Less than 30 minutes
Degradation
Predominantly by blood proteases
Tissue Specificity
Targets thymus and immune-related tissues
⚗️
Peptide Details
Molecular Weight
857
Formula
C33H54N12O15
Sequence
Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
⚖️
Legal Status & Regulatory
RegionStatus
EUNot Approved
FDANot Approved
CanadaNot Approved
AustraliaNot Approved
Storage Instructions
Lyophilized (Powder)
Store lyophilized powder at 2-8°C
Reconstituted (Mixed)
After reconstitution, maintain at 2-8°C and use within 21 days. Thymalin is relatively stable but protect from light exposure.