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Vesugen

peptide · headlineResearch use only

Regulates gene expression of vascular wall endothelial cells

Summary

Vesugen is a synthetic peptide studied for its potential vascular-regulatory effects. It is derived from DNA-regulating peptide complexes and has been evaluated in Russia for its effects on endothelial function and cardiovascular aging.

How it works

  • Regulates gene expression of vascular wall endothelial cells
  • Supports extracellular matrix remodeling and vascular elasticity
  • May stabilize microcirculation and reduce endothelial permeability

Dosing

  • unit: mg
    low dose: 0.5
    frequency: Once daily for 10–20 days
    high dose: 2
    standard dose: 1
    administration route: Subcutaneous (SQ)

Cycling

  • Administer daily for 10–20 days. Repeat cycle every 3–6 months for vascular maintenance or recovery.

Side effects

common: ["Mild nausea (<5%), occasional headaches (<3%), minor digestive upset (user-reported)"]
warnings: ["Drug interactions with statins/ACE inhibitors untested"]

Chemistry & PK

sequence: Lys-Glu-Asp
half life: Estimated 3–4 hours
degradation: Metabolized by renal and hepatic peptidases
molecular weight: 390.39
molecular formula: C15H26N4O8
tissue specificity: Acts primarily on capillaries, vascular smooth muscle, and endothelial tissues

Verified citations

2 · PubMed-checked
  • Peptides tissue-specifically stimulate cell differentiation during their aging.mechanismPMID 22808515
  • Effect of synthetic peptides on aging of patients with organic brain syndrome.clinicalPMID 26390612

Used for

No condition evidence rows yet.

Legal / compounding

Research use only

Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.