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← Compounds

Micronized progesterone

hormone · comparatorFDA-approved

Progesterone receptor agonism; GABAergic sleep metabolite

Summary

Micronized progesterone — endometrial protection alongside estrogen, with a sedative benefit for sleep.

How it works

  • Progesterone receptor agonism
  • GABAergic metabolite (sleep)

Dosing

  • unit: mg
    frequency: QHS
    high dose: 200
    standard dose: 100
    administration route: Oral

Cycling

  • Continuous or cyclic

Side effects

common: ["Sedation","Dizziness"]
warnings: ["Note: GLP-1 delayed gastric emptying alters oral absorption/timing"]

Verified citations

2 · PubMed-checked
  • Diagnostic and therapeutic use of oral micronized progesterone in endocrinology.reviewPMID 38652231 ↗
  • Oral micronized progesterone for perimenopausal night sweats and hot flushes: Phase III RCT.clinicalPMID 37277418 ↗

Used for

Legal / compounding

FDA-approved

Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.