BPC-157

BPC-157 is a synthetic peptide derived from a sequence found in human gastric juice. It has been extensively studied in rodent models for its effects on healing, angiogenesis, and inflammation reduction. Though widely researched, it is not approved for human or veterinary use.

• Promotes angiogenesis
• Enhances nitric oxide production
• Upregulates VEGF signaling
• Increases GH receptor expression in tendon fibroblasts
• Stabilizes microvascular endothelium
• Accelerates fibroblast migration and F-actin formation

• unit: mg

  low dose: 0.25

  frequency: 2x daily

  high dose: 1

  standard dose: 0.5

  administration route: Subcutaneous (SQ)

• unit: mg

  low dose: 0.5

  frequency: daily

  high dose: 2

  standard dose: 1

  administration route: Oral

• Daily injections for 4–6 weeks, then reassess healing response.

common: ["Anxiety and panic attacks (frequently user-reported)","Nausea, fatigue, loss of appetite (user-reported)","Insomnia and sleep disturbances (user-reported)","Heart palpitations (user-reported)"]

warnings: ["Depression and anhedonia (user-reported)","Contamination risk: 30% of online peptides contain incorrect sequences; 65% exceed endotoxin thresholds (quality study)"]

sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

half life: Estimated ~4 hours (based on animal data; no human PK studies published).

degradation: Predominantly metabolized in the liver and intestines.

molecular weight: 1419.53552

molecular formula: C62H98N16O22

tissue specificity: Demonstrated efficacy in gastric tissues and musculoskeletal system.

• The promoting effect of pentadecapeptide BPC 157 on tendon healing.mechanismPMID 21030672 ↗
• BPC 157 and its role in accelerating musculoskeletal soft tissue healing.reviewPMID 30915550 ↗
• Multifunctionality and Possible Medical Application of the BPC 157 Peptide.reviewPMID 40005999 ↗